Once you fight your way through the Zeebetites to Mother Brain, you must first blow open her container. Use 5 Super Missiles: if you shoot fast enough, the fourth Super Missile will destroy the container, and the fifth Super Missile will hit Mother Brain directly. Once the glass shatters, Mother Brain will begin to store up energy, open her eyeball, and shoot a powerful energy beam. One hit from this beam will take off 50 energy. To avoid the beam: there are two platforms that Samus can stand on, one closer to Mother Brain, and one further away. Stand on the one further away, and when the beam comes out, jump over it, onto the closer platform. Kneel and immediately shoot a Super Missile or a few normal Missiles to harm her. She will then immediately shoot another beam. Jump straight up to avoid it, land, and then jump back to the previous platform. Keep repeating this pattern (all the while freezing or destroying the oncoming Rinkas) until she dies. If you fall into the acid below, just try to get out of it as quickly as you can by using the Power Grip, and climb up on the platform furthest away from Mother Brain. When she is defeated, Samus must immediately escape from Tourian using the shaft located behind Mother Brain's container. You have two minutes. Good luck!
